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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP14
All Species:
39.39
Human Site:
S467
Identified Species:
57.78
UniProt:
P54578
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54578
NP_001032411.1
494
56069
S467
P
E
D
I
L
R
L
S
G
G
G
D
W
H
I
Chimpanzee
Pan troglodytes
P60051
493
55922
S467
P
E
D
I
L
R
L
S
G
G
G
D
W
H
I
Rhesus Macaque
Macaca mulatta
XP_001090667
458
52239
S432
P
E
D
I
L
R
L
S
G
G
G
D
W
H
I
Dog
Lupus familis
XP_537306
545
61461
S518
P
E
D
I
L
R
L
S
G
G
G
D
W
H
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMA1
493
55983
S466
P
E
D
I
L
R
L
S
G
G
G
D
W
H
I
Rat
Rattus norvegicus
NP_001008302
493
55958
S466
P
E
D
I
L
R
L
S
G
G
G
D
W
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519267
431
48760
G405
D
D
I
L
R
L
S
G
G
G
D
W
H
I
A
Chicken
Gallus gallus
XP_419150
492
55612
S465
P
E
D
I
L
R
L
S
G
G
G
D
W
H
I
Frog
Xenopus laevis
Q6GNI6
523
60030
T472
A
V
V
N
H
Q
G
T
L
E
S
G
H
Y
T
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
A478
Q
W
F
K
C
D
D
A
I
I
T
K
A
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609377
475
53689
D448
E
V
S
A
V
A
T
D
E
I
L
R
L
S
G
Honey Bee
Apis mellifera
XP_395043
497
56311
S464
S
E
E
V
L
K
L
S
G
G
G
D
W
H
C
Nematode Worm
Caenorhab. elegans
Q17361
489
55859
S442
E
E
A
I
L
K
T
S
G
G
G
D
W
H
S
Sea Urchin
Strong. purpuratus
XP_786966
516
58357
S478
S
E
D
I
L
K
L
S
G
G
G
D
W
H
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q949Y0
482
53677
R454
D
D
N
P
S
M
Q
R
E
E
D
I
T
K
L
Baker's Yeast
Sacchar. cerevisiae
P43593
499
57092
E473
D
D
K
V
S
V
V
E
K
E
K
I
E
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
92.5
89.9
N.A.
96.7
96.5
N.A.
80.3
90.4
21.4
20.1
N.A.
54.6
61.7
41.9
61
Protein Similarity:
100
99.8
92.7
90.2
N.A.
98.5
98.7
N.A.
83.8
94.9
39
38.7
N.A.
71.2
80.2
61.1
76.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
0
6.6
N.A.
0
66.6
66.6
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
100
20
13.3
N.A.
6.6
86.6
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.5
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.9
46.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
0
7
0
7
0
0
0
0
7
0
7
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
13
% C
% Asp:
19
19
50
0
0
7
7
7
0
0
13
63
0
0
0
% D
% Glu:
13
63
7
0
0
0
0
7
13
19
0
0
7
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
7
7
69
69
63
7
0
0
7
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
13
63
0
% H
% Ile:
0
0
7
57
0
0
0
0
7
13
0
13
0
7
50
% I
% Lys:
0
0
7
7
0
19
0
0
7
0
7
7
0
7
0
% K
% Leu:
0
0
0
7
63
7
57
0
7
0
7
0
7
0
13
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
44
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
44
0
7
0
0
0
7
0
0
0
% R
% Ser:
13
0
7
0
13
0
7
63
0
0
7
0
0
19
7
% S
% Thr:
0
0
0
0
0
0
13
7
0
0
7
0
7
0
7
% T
% Val:
0
13
7
13
7
7
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
7
63
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _